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Cerebellum. 2013 Oct;12(5):738-57. doi: 10.1007/s12311-013-0464-0.

Consensus paper: current views on the role of cerebellar interpositus nucleus in movement control and emotion.

Author information

1
Department of Bio-Medical Sciences, Section of Physiology, University of Catania, Viale Andrea Doria 6, 95125, Catania, Italy. perciava@unict.it

Abstract

In the present paper, we examine the role of the cerebellar interpositus nucleus (IN) in motor and non-motor domains. Recent findings are considered, and we share the following conclusions: IN as part of the olivo-cortico-nuclear microcircuit is involved in providing powerful timing signals important in coordinating limb movements; IN could participate in the timing and performance of ongoing conditioned responses rather than the generation and/or initiation of such responses; IN is involved in the control of reflexive and voluntary movements in a task- and effector system-dependent fashion, including hand movements and associated upper limb adjustments, for quick effective actions; IN develops internal models for dynamic interactions of the motor system with the external environment for anticipatory control of movement; and IN plays a significant role in the modulation of autonomic and emotional functions.

PMID:
23564049
DOI:
10.1007/s12311-013-0464-0
[Indexed for MEDLINE]

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