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Indian J Nucl Med. 2011 Oct;26(4):185-7. doi: 10.4103/0972-3919.106701.

Poor Tc-99m dimercaptosuccinic acid uptake, re-evaluation with Tc-99m MAG3 scintigraphy in Lowe syndrome.

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1
Department of Nuclear Medicine, Ministry of Health, Ankara Training and Research Hospital, Ulucanlar, Altindag, Ankara, Turkey.

Abstract

Tc-99m dimercaptosuccinic acid (DMSA) is filtered through the glomeruli and reabsorbed by the proximal tubules as low molecular weight proteins. In Lowe syndrome this mechanism is impaired and so poor DMSA uptake is seen. Poor DMSA uptake was shown in very few studies, but none mentioned normal Tc-99m MAG3 uptake. In this case, the patient had poor DMSA uptake, normal MAG3 uptake and a neurogenic bladder in anterior to the left kidney that attenuates left kidney.

KEYWORDS:

Lowe syndrome; Tc-99m MAG3; Tc-99m dimercaptosuccinic acid

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