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Exerc Sport Sci Rev. 2013 Jul;41(3):169-73. doi: 10.1097/JES.0b013e318292f3d5.

Anabolic resistance of muscle protein synthesis with aging.

Author information

1
Department of Human Movement Sciences, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands.

Abstract

Aging has been associated with a reduced muscle protein synthetic response to protein intake, termed "anabolic resistance." Physical activity performed before protein intake increases the use of protein-derived amino acids for postprandial muscle protein accretion in senescent muscle. Thus, the level of habitual physical activity may be fundamental to maintain the anabolic responsiveness to protein intake with aging.

PMID:
23558692
DOI:
10.1097/JES.0b013e318292f3d5
[Indexed for MEDLINE]

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