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Fertil Steril. 2013 Jul;100(1):214-8. doi: 10.1016/j.fertnstert.2013.03.010. Epub 2013 Apr 1.

Phenotypic comparison of Caucasian and Asian women with polycystic ovary syndrome: a cross-sectional study.

Author information

1
Department of Obstetrics & Gynecology, Cedars Sinai Medical Center, Los Angeles, California 90048, USA. erica.wang@cshs.org

Abstract

OBJECTIVE:

To determine whether manifestations of polycystic ovary syndrome (PCOS), particularly androgen excess, differ between Caucasian and Asian women in the San Francisco Bay Area.

DESIGN:

Cross-sectional study.

SETTING:

Multidisciplinary PCOS clinic at a tertiary academic center.

PATIENT(S):

121 Caucasian and 28 Asian women, aged 18-44, examined between 2006 and 2011 with PCOS verified by a reproductive endocrinologist and dermatologist according to the Rotterdam criteria.

INTERVENTION(S):

Transvaginal ultrasounds, comprehensive dermatologic exams, and serum testing.

MAIN OUTCOME MEASURE(S):

Hirsutism defined as a modified Ferriman-Gallwey (mFG) score ≥ 8, acne, androgenic alopecia, and biochemical hyperandrogenism.

RESULT(S):

Caucasian and Asian women had a similar prevalence of all measures of androgen excess. Both groups had similar total mFG scores and site-specific mFG scores, except Asian women had a lower site-specific mFG score for the chest. Although Asian women were more likely to use laser hair removal, the results were unchanged when the women with a history of laser hair removal were excluded.

CONCLUSION(S):

Caucasian and Asian women with PCOS living in the same geographic region had a similar prevalence of hirsutism as well as other markers for androgen excess. Further studies are necessary to evaluate the need for ethnic-specific mFG scores in women with PCOS.

[Indexed for MEDLINE]

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