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Ther Adv Hematol. 2011 Oct;2(5):309-16. doi: 10.1177/2040620711410774.

Myeloid sarcoma: current approach and therapeutic options.

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Division of Hematology, Chaim Sheba Medical Center Tel Hashomer, Israel and Hematology/Oncology, Cedars-Sinai Medical Center, Los Angeles CA, USA.


Myeloid sarcoma is a rare disease that can present as an isolated extramedullary leukemic tumor, concurrently with or at relapse of acute myeloid leukemia. Owing to the rarity of this disorder, most of the literature comprises small retrospective studies and case reports. The aim of this review is to summarize the current published data regarding the clinical presentation, morphological, cytogenetic and molecular features, prognosis and treatment of myeloid sarcoma.


acute myeloid leukemia; myeloid sarcoma; prognosis; therapy

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