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J Clin Microbiol. 2013 Jun;51(6):1945-7. doi: 10.1128/JCM.00806-13. Epub 2013 Apr 3.

Analytical evaluation of GeneXpert CT/NG, the first genetic point-of-care assay for simultaneous detection of Neisseria gonorrhoeae and Chlamydia trachomatis.

Author information

1
Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia. sepehr.tabrizi@thewomens.org.au

Abstract

GeneXpert CT/NG was evaluated with 372 characterized bacterial strains. Sensitivity of 10 genome copies/reaction was obtained for both agents. Four Neisseria mucosa and two Neisseria subflava isolates were positive for one of two gonococcal targets; however, the assay flagged all as negative. The assay was analytically highly sensitive and specific.

PMID:
23554203
PMCID:
PMC3716077
DOI:
10.1128/JCM.00806-13
[Indexed for MEDLINE]
Free PMC Article
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