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Cancer Epidemiol Biomarkers Prev. 2013 Apr;22(4):553-60. doi: 10.1158/1055-9965.EPI-12-1406.

Human papillomavirus infection and the multistage carcinogenesis of cervical cancer.

Author information

1
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., Room 7012, Rockville, MD 20852, USA. schiffmm@mail.nih.gov

Abstract

This short review outlines our understanding of cervical cancer precursors, concentrating on the central etiologic role of persistent human papillomavirus infection. The stages of cervical carcinogenesis are better understood than for most other major cancers, providing a successful cancer etiology and prevention model.

PMID:
23549399
PMCID:
PMC3711590
DOI:
10.1158/1055-9965.EPI-12-1406
[Indexed for MEDLINE]
Free PMC Article

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