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Ophthalmologica. 2013;229(3):173-8. doi: 10.1159/000348740. Epub 2013 Mar 27.

Clinical pattern of toxoplasmic retinochoroiditis in a Spanish referral center.

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Department of Ophthalmology, Hospital Clinic de Barcelona, University of Barcelona, Barcelona, Spain.



To analyze the clinical pattern of ocular toxoplasmosis in a referral center in Spain.


The medical records of consecutive patients with ocular toxoplasmosis admitted from a single referral center for uveitis in Barcelona (Spain) were retrospectively analyzed between January 2005 and January 2011.


One hundred and thirteen eyes from 113 patients (74 Spanish and 39 South American) with active ocular toxoplasmosis were analyzed with a 12-month follow-up. Final BCVA ≤ 20/200 was found in 30 eyes (26.5%). The most frequent complications were macular edema (16.8%) and epiretinal membrane (11.5%). Anterior chamber cell scores of ≥ 2+ (p = 0.003), vitreous cell scores of ≥ 2+ (p = 0.001), and the presence of cataracts (p = 0.047) or serous retinal detachment (p = 0.008) were more common among the South American than Spanish cohort. Active macular lesions (p < 0.001) with an initial BCVA ≤ 20/200 (p < 0.001) and advanced age (p = 0.019) were predictors for final BCVA ≤ 20/200, whereas female gender (p = 0.021) and an initial BCVA ≤20/200 (p = 0.045) were predictors for ocular complications. Moreover, a BCVA ≤ 20/200 (p < 0.001) and a vitreous cell score of ≥ 2+ (p = 0.045) at the initial examination were predictors of an eventual need for ocular surgery.


The clinical features of ocular toxoplasmosis in Spanish patients differ from those of South American patients. In general, active macular lesions with an initial BCVA ≤ 20/200 and advanced age were shown to be predictors for final BCVA ≤ 20/200 in our patient cohort.

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