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J Neurosci Rural Pract. 2013 Jan;4(1):39-41. doi: 10.4103/0976-3147.105608.

Wernicke's encephalopathy and central pontine myelinolysis in hyperemesis gravidarum.

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Department of Neurology, Faculty of Medicine, Thammasart University, Thailand.


A pregnant woman, who had been suffering from hyperemesis gravidarum, presented with alteration of consciousness, ocular nystagmus and ataxia. Magnetic Resonance Imaging of the brain showed typical findings of Wernicke's encephalopathy and central pontine myelinolysis. The clinical features responded dramatically to thiamine supplementation.


Central pontine myelinolysis; Wernicke's encephalopathy; hyperemesis gravidarum

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