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Sensors (Basel). 2013 Mar 28;13(4):4170-91. doi: 10.3390/s130404170.

Quantitative phase imaging techniques for the study of cell pathophysiology: from principles to applications.

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1
Department of Physics, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea. kyeo@kaist.ac.kr

Abstract

A cellular-level study of the pathophysiology is crucial for understanding the mechanisms behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques show promises for the cellular-level understanding of the pathophysiology of diseases. To provide important insight on how the QPI techniques potentially improve the study of cell pathophysiology, here we present the principles of QPI and highlight some of the recent applications of QPI ranging from cell homeostasis to infectious diseases and cancer.

PMID:
23539026
PMCID:
PMC3673078
DOI:
10.3390/s130404170
[Indexed for MEDLINE]
Free PMC Article
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