Format

Send to

Choose Destination
See comment in PubMed Commons below
J Neurosci. 2013 Mar 27;33(13):5736-49. doi: 10.1523/JNEUROSCI.4432-12.2013.

Oscillatory entrainment of primary somatosensory cortex encodes visual control of tactile processing.

Author information

1
Developmental Neurophysiology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany. kay.sieben@zmnh.uni-hamburg.de

Abstract

Optimal behavior relies on the successful integration of complementary information from multiple senses. The neural mechanisms underlying multisensory interactions are still poorly understood. Here, we demonstrate the critical role of neural network oscillations and direct connectivity between primary sensory cortices in visual-somatosensory interactions. Extracellular recordings from all layers of the barrel field in Brown Norway rats in vivo showed that bimodal stimulation (simultaneous light flash and whisker deflection) augmented the somatosensory-evoked response and changed the power of induced network oscillations by resetting their phase. Anatomical tracing revealed sparse direct connectivity between primary visual (V1) and somatosensory (S1) cortices. Pharmacological silencing of V1 diminished but did not abolish cross-modal effects on S1 oscillatory activity, while leaving the early enhancement of the evoked response unaffected. Thus, visual stimuli seem to impact tactile processing by modulating network oscillations in S1 via corticocortical projections and subcortical feedforward interactions.

PMID:
23536087
DOI:
10.1523/JNEUROSCI.4432-12.2013
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Support Center