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Nat Genet. 2013 Apr;45(4):349-51. doi: 10.1038/ng.2582.

Public health implications from COGS and potential for risk stratification and screening.

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1
PHG Foundation (Foundation for Genomics and Population Health), Cambridge, UK. hilary.burton@phgfoundation.org

Abstract

The PHG Foundation led a multidisciplinary program, which used results from COGS research identifying genetic variants associated with breast, ovarian and prostate cancers to model risk-stratified prevention for breast and prostate cancers. Implementing such strategies would require attention to the use and storage of genetic information, the development of risk assessment tools, new protocols for consent and programs of professional education and public engagement.

PMID:
23535723
DOI:
10.1038/ng.2582
[Indexed for MEDLINE]
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