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Pediatr Dermatol. 2015 Jan-Feb;32(1):113-7. doi: 10.1111/pde.12129. Epub 2013 Mar 28.

Pyoderma gangrenosum associated with an aseptic splenic abscess in a patient with neurofibromatosis.

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1
Indiana University School of Medicine, Indianapolis, Indiana.

Abstract

Pyoderma gangrenosum (PG) is a painful, ulcerating neutrophilic dermatosis commonly associated with a variety of underlying systemic conditions. We report a child with neurofibromatosis-1 (NF-1) and an aseptic splenic abscess who developed multifocal PG in areas of iatrogenic skin trauma. There is no clinical evidence or theoretical basis to suggest a causal relationship between NF-1 and PG. Systemic corticosteroid and cyclosporine therapy led to complete resolution of the lesions.

PMID:
23535023
DOI:
10.1111/pde.12129
[Indexed for MEDLINE]
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