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Trop Med Health. 2012 Dec;40(4):149-53. doi: 10.2149/tmh.2012-27. Epub 2013 Jan 19.

Retinal involvement of Paracoccioidomycosis: A Case Report.

Author information

1
Department of Ophthalmology, University of São Paulo, School of Medicine (Hospital das Clínicas da Universidade de São Paulo- São Paulo- HC-USP)- Brazil ; Department of Ophthalmology, Santa Casa de São Paulo, Brazil.

Abstract

PURPOSE:

to describe the clinicopathologic features and treatment of a rare case of systemic paracoccidioidomycosis with choroidal and retinal involvement.

DESIGN:

retrospective interventional case report.

PARTICIPANT:

A 36-year-old young man with visual impairment in left eye with anterior uveitis and presence of whitish perimacular choroidal nodule, multiple underlying whitish spots and mid-periphery exudative retinal detachment. A primary extensive work-up for systemic infectious, autoimmune, neoplasic or inflammatory conditions was performed and high-resolution computer tomography scan demonstrated asymmetric parietal thickening of the trachea and bilateral diffuse multiple lobular opacities. Pulmonary bronchoscopy/biopsy of larynx, trachea and bronchial tube were also performed. Histopathological evaluation showed characteristic of Paracoccidioidomycosis.

INTERVENTION:

Patient was treated with oral sulphadiazine (1.5 g/day).

MAIN OUTCOME MEASURES:

Anterior uveitis, retinal examination, histopathological evaluation and primary clinical outcome were observed during systemic treatment.

RESULTS:

After 3 months of irregular treatment, choroidal lesions decreased in size forming atrophic scars and fibrotic spots; however visual acuity did not show any improvement.

CONCLUSION:

We report a rare case of systemic paracoccidioidomycosis with choroidal and retinal involvement treated with oral sulphadiazine.

KEYWORDS:

Paracoccioidomycosis; eye; retina

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