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Chem Commun (Camb). 2013 May 4;49(34):3570-2. doi: 10.1039/c3cc41337c.

Vinylic amino group activation: a new and general strategy leading to functionalized fused heteroaromatics.

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1
Dr Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India.

Abstract

A conceptually new and general strategy has been developed for the construction of a benzimidazole or a benzoxazole ring fused with isoquinolinone affording a diverse and unique class of small molecules as potential and novel inhibitors of PDE4.

PMID:
23525274
DOI:
10.1039/c3cc41337c
[Indexed for MEDLINE]
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