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Drug Discov Ther. 2013 Feb;7(1):24-8.

New phenolic compounds from the twigs of Artocarpus heterophyllus.

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Department of Natural Product Chemistry, Shandong University, Ji'nan, Shandong, China.


Two new chalcones, artocarpusins A and B (1 and 2), one new flavone, artocarpusin C (3), one new 2-arylbenzofuran derivative, artocarstilene A (4), and 15 flavonoids were isolated from the twigs of Artocarpus heterophyllus. Their structures were established on the basis of extensive spectroscopic analysis. Compounds 9 and 16 showed moderate inhibitory activity on the proliferation of the PC-3 and H460 cell lines.

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