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Plant Signal Behav. 2013 Jun;8(6):e24226. doi: 10.4161/psb.24226. Epub 2013 Mar 21.

DAR2 acts as an important node connecting cytokinin, auxin, SHY2 and PLT1/2 in root meristem size control.

Author information

1
State Key Laboratory of Plant Cell and Chromosome Engineering; Institute of Genetics and Developmental Biology; Chinese Academy of Sciences; Beijing, China.

Abstract

Cytokinin and auxin antagonistically affect cell proliferation and differentiation and thus regulate root meristem size by influencing the abundance of SHORT HYPOCOTYL2 (SHY2/IAA3). SHY2 affects auxin distribution in the root meristem by repressing the auxin-inducible expression of PIN-FORMED (PIN) auxin transport genes. The PLETHORA (PLT1/2) genes influence root meristem growth by promoting stem cells and transit-amplifying cells. However, the factors connecting cytokinin, auxin, SHY2 and PLT1/2 are largely unknown. In a recent study, we have shown that the DA1-related protein 2 (DAR2) acts downstream of cytokinin and SHY2 but upstream of PLT1/2 to affect root meristem size. Here, we discuss the possible molecular mechanisms by which Arabidopsis DAR2 controls root meristem size.

KEYWORDS:

DAR2; auxin; cytokinin; root meristem size; stem cell niche activity

PMID:
23518585
PMCID:
PMC3907457
DOI:
10.4161/psb.24226
[Indexed for MEDLINE]
Free PMC Article
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