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Diagn Microbiol Infect Dis. 2013 Jun;76(2):244-7. doi: 10.1016/j.diagmicrobio.2013.02.008. Epub 2013 Mar 19.

Contribution of molecular diagnosis to congenital toxoplasmosis.

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Mycology-Parasitology Laboratory, EA4547-BDEEP, CIIL, Faculté de Médecine, Univ Nord de France (UDSL), CHRU de Lille, France.


We evaluated the performance of three real-time polymerase chain reaction (PCR) assays on 73 samples from mothers and children with congenital toxoplasmosis. PCR assays had significantly higher sensitivity in prenatal period than in birth period when targeting the 529-bp repeat element (81.3% versus 36.0%) or the B1 gene (64.6% versus 20.0%).

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