Format

Send to

Choose Destination
See comment in PubMed Commons below
J Mycol Med. 2012 Sep;22(3):211-6. doi: 10.1016/j.mycmed.2012.04.006. Epub 2012 Aug 9.

Anti-Candida zeylanoides activity of some Iranian plants used in traditional medicine.

Author information

1
Faculty of Veterinary Medicine, University of Mazandaran, 24th, aftab Imam Khomeini Street, Amol 46168-49767, Iran. hshokri@umz.ac.ir

Abstract

OBJECTIVE:

To assess anti-Candida zeylanoides activity of the essential oils (EOs) of five Iranian medicinal plants and to determine the different components of the EOs.

METHODS:

Anti-C. zeylanoides effects of the EOs and reference drugs were determined by disc diffusion method. The EOs from Trachyspermum copticum, Zataria multiflora, Nigella sativa, Ziziphora clinopodiodes and Heracleum persicum were analyzed by gas chromatography/mass spectroscopy (GC/MS).

RESULTS:

The mean values of inhibition zones were found to be more than 60mm for T. copticum, 56.7 mm for Z. multiflora, 40.8mm for N. sativa, 33.7 mm for Z. clinopodiodes and 18.7 mm for H. persicum. In GC/MS analysis, thymol (63.4%), carvacrol (61%), trans anthol (39%), pulegone (37%) and hexyl butyrate (30.2%) were found to be the major components of T. copticum, Z. multiflora, N. sativa, Z. clinopodiodes and H. persicum, respectively.

CONCLUSION:

The EOs showed strong anti-C. zeylanoides activities, which strengthen the potential use of these substances for the treatment of candidiasis.

PMID:
23518076
DOI:
10.1016/j.mycmed.2012.04.006
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center