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Gen Hosp Psychiatry. 2013 Sep-Oct;35(5):575.e7-8. doi: 10.1016/j.genhosppsych.2013.02.004. Epub 2013 Mar 19.

Electroconvulsive therapy-induced Wolff-Parkinson-White syndrome: a case report.

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Department of Psychiatry, National Defense Medical College, Saitama 3598513, Japan.



Wolff-Parkinson-White (WPW) syndrome is characterized by premature ventricular excitation due to the presence of an abnormal accessory pathway. Electrocardiography (ECG) of patients with WPW syndrome portrays a short PR interval and a wide QRS interval with a delta wave.


Herein, we report the case of a patient with schizophrenia who developed a wide QRS interval with a delta wave immediately following electroconvulsive therapy (ECT).


Initially, the delta wave disappeared within 2 days after ECT. However, the duration of the delta wave increased exponentially to 4 months when ECT was repeated.


Although the patient's cardiocirculatory dynamics remained normal, we continued to monitor her ECG until the delta wave disappeared because WPW syndrome can lead to serious arrhythmia.


Arrhythmia; Autonomic nervous system; Electroconvulsive therapy; Schizophrenia; WPW syndrome

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