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J Rehabil Res Dev. 2012;49(10):1467-78.

Preliminary investigation of residual-limb fluid volume changes within one day.

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  • 1Department of Bioengineering, Foege N430J, 1705 Pacific St, University of Washington, Seattle, WA 98195, USA.


The purpose of this research was to investigate rates of residual-limb fluid volume change within one day for people with transtibial limb loss. Rates of fluid volume change during 30 min test sessions of sitting, standing, and walking activities were measured twice a day, once in the morning and once in the afternoon, on 12 regular prosthesis users with the use of bioimpedance analysis. Between test sessions, all subjects consumed food and drink, and subject activity ranged from low to high. The rate of fluid volume change within sessions ranged from -8.5 to 5.9 %/h (median: -2.2%/h). The rate of fluid volume change between sessions ranged from -2.7 to 0.9 %/h (median: -1.0%/h). The between-session rate of fluid volume change correlated highly with afternoon within-session rates of change (r = 0.9) but was not well correlated with morning within-session rates of change (r = 0.8). Subjects with peripheral arterial complications showed greater fluid volume loss rates during test sessions than between sessions. Rate of fluid volume change may be affected by sitting, standing, and walking activities; presence of peripheral arterial complications; being female; time since amputation; and wearing the socket without doffing for extended periods.

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