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J Pediatr Endocrinol Metab. 2013;26(5-6):561-4. doi: 10.1515/jpem-2012-0321.

Diabetic ketoacidosis with cerebral hemorrhage and alpha coma in an adolescent female.

Author information

1
Section of Endocrinology and Diabetes, St. Christopher's Hospital for Children, Drexel University College of Medicine, Philadelphia, PA 19134, USA.

Abstract

BACKGROUND:

Diabetic ketoacidosis (DKA) is one of the most common and harmful complications of type 1 diabetes in children. The neurologic morbidities, including seizure activity, motor/sensory deficit, and coma, can be seen secondary to cerebral edema, hemorrhage, or ischemia. Alpha-frequency is a normal 8-13 Hz physiologic electroencephalogram rhythm that is seen most prominently in the occipital region of awake people and is augmented by eye closure. In the comatose patient, alpha-rhythm is not usually seen. Alpha-frequency coma (AC) is a rare finding in comatose patients and is generally associated with a poor prognosis.

CASE REPORT:

We report an adolescent with severe DKA, intraparenchymal cerebral hemorrhage, and AC, who had a rapid resolution of the neurologic symptoms.

CONCLUSIONS:

Similar to other reported cases, our case suggests that the prognosis for patients with AC may not be always poor when it is associated with DKA.

PMID:
23515102
DOI:
10.1515/jpem-2012-0321
[Indexed for MEDLINE]

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