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J Med Case Rep. 2013 Mar 19;7:83. doi: 10.1186/1752-1947-7-83.

Aphonia induced by simultaneous bilateral ischemic infarctions of the putamen nuclei: a case report and review of the literature.

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Department of Neurology, Baltimore Veterans Affairs Medical Center and University of Maryland School of Medicine, Baltimore, MD 21201, USA.



Isolated aphonia induced by acute stroke is a rare phenomenon with only a few cases reported in the literature.


We report an unusual case of a 44-year-old African-American man with a history of hypertension, smoking and cocaine use who developed acute aphonia secondary to simultaneous ischemic infarctions of the bilateral putamen nuclei.


We describe the clinical presentation of acute aphonia induced by bilateral putamen nuclei ischemic infarctions, correlating clinical symptoms with injury localization. We further highlight the anatomic and functional organization of the neural pathways involved.

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