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Muscle Nerve. 2013 May;47(5):702-10. doi: 10.1002/mus.23631. Epub 2013 Mar 16.

Shock wave treatment improves nerve regeneration in the rat.

Author information

1
Department of Neurophysiology, Centre for Biomedicine and Medical Technology Mannheim, Ruprecht Karls University Heidelberg, Ludolf Krehl Strasse 13-17, 68167 Mannheim, Germany. siegfried.mense@medma.uni-heidelberg.de

Abstract

INTRODUCTION:

The aims of the experiments were to: (1) determine whether low-energy shock wave treatment accelerates the recovery of muscle sensitivity and functionality after a nerve lesion; and (2) assess the effect of shock waves on the regeneration of injured nerve fibers.

METHODS:

After compression of a muscle nerve in rats the effects of shock wave treatment on the sequelae of the lesion were tested. In non-anesthetized animals, pressure pain thresholds and exploratory activity were determined. The influence of the treatment on the distance of nerve regeneration was studied in immunohistochemical experiments.

RESULTS:

Both behavioral and immunohistochemical data show that shock wave treatment accelerates the recovery of muscle sensitivity and functionality and promotes regeneration of injured nerve fibers.

CONCLUSION:

Treatment with focused shock waves induces an improvement of nerve regeneration in a rodent model of nerve compression.

PMID:
23505053
DOI:
10.1002/mus.23631
[Indexed for MEDLINE]

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