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Biomed Opt Express. 2013 Mar 1;4(3):460-5. doi: 10.1364/BOE.4.000460. Epub 2013 Feb 20.

Imaging myocardial fiber orientation using polarization sensitive optical coherence tomography.

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Department of Biological Engineering, University of Missouri, Columbia, MO 65201, USA.


Knowledge of myocardial fiber architecture is essential towards understanding heart functions. We demonstrated in this study a method to map cardiac muscle structure using the local optical axis obtained from polarization-sensitive optical coherence tomography (PSOCT). An algorithm was developed to extract the true local depth-resolved optical axis, retardance, and diattenuation from conventional round-trip results obtained in a Jones matrix-based PSOCT system. This method was applied to image the myocardial fiber orientation in a bovine heart muscle sample.


(110.4500) Optical coherence tomography; (230.5440) Polarization-selective devices

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