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Fertil Steril. 2013 Jun;99(7):1951-7. doi: 10.1016/j.fertnstert.2013.02.017. Epub 2013 Mar 15.

Racial differences in fibroid prevalence and ultrasound findings in asymptomatic young women (18-30 years old): a pilot study.

Author information

1
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA. erica-marsh@northwestern.edu

Abstract

OBJECTIVE:

1) To determine the prevalence of fibroids in asymptomatic young black and white women (ages 18-30 y); 2) to determine other differences in uterine and adnexal anatomy; and 3) to obtain preliminary data for sample size calculations.

DESIGN:

Pilot cross-sectional study.

SETTING:

Academic medical center.

PATIENT(S):

One hundred one nonparous black and white women, ages 18-30 years, with no known diagnosis of fibroids or clinically suggestive symptoms.

INTERVENTION(S):

A transvaginal ultrasound was performed in the follicular phase in all subjects.

MAIN OUTCOME MEASURE(S):

1) Presence of fibroids; 2) endometrial thickness; 3) ovarian findings.

RESULT(S):

Of the 101 participants (mean age 24.5 ± 3.5 y), 43% self-identified as black and 57% as white. The prevalence of ultrasound-diagnosed fibroids was 15% overall (26% in black women and 7% in white women). The mean fibroid size was 2.3 ± 2.1 cm. There was a significant difference in endometrial thickness between races, even after adjusting for contraception use and fibroid presence.

CONCLUSION(S):

Racial differences in fibroid prevalence exist even before women become symptomatic. Findings of thicker endometrium in black women could have clinical implications and warrants further investigation.

Comment in

PMID:
23498888
PMCID:
PMC4465811
DOI:
10.1016/j.fertnstert.2013.02.017
[Indexed for MEDLINE]
Free PMC Article

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