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Psychiatry Res. 2013 Nov 30;210(1):55-61. doi: 10.1016/j.psychres.2013.02.007. Epub 2013 Mar 13.

Apathy, poor verbal memory and male gender predict lower psychosocial functioning one year after the first treatment of psychosis.

Author information

1
Oslo University Hospital, Ulleval, 0407 Oslo, Norway. Electronic address: ann.farden@medisin.uio.no.

Abstract

BACKGROUND:

Apathy is a negative symptom associated with poor psychosocial functioning in schizophrenia but has not been sufficiently studied as predictor of poor functioning in first episode psychosis (FEP).

OBJECTIVE:

The main aim of the current study was to evaluate if apathy predicts poor functioning after 1 year in FEP patients in the context of other clinical variables with influence on outcome.

METHOD:

Sixty-four FEP patients completed an extensive clinical and neuro-psychological test battery at baseline and 1-year follow-up. Symptoms were assessed with the Positive and Negative Syndrome scale (PANSS), apathy with the shortened Apathy Evaluation Scale (AES-C-12) and psychosocial functioning with the functioning score from the split version of the Global Assessment of Functioning scale (GAF-F).

RESULTS:

High levels of apathy, poor verbal memory and being male were the baseline variables that best predicted poor functioning at 1-year follow-up, explaining 34% of the variance in GAF-F. When PANSS negative factor was included in the analysis, the significance of AES-C-12 diminished.

CONCLUSION:

These findings points to a robust role for apathy among the negative symptoms in the development of persisting psychosocial dysfunction in FEP and supports the current effort in targeting motivation to improve functioning.

KEYWORDS:

Apathy; Functional outcome; Male gender; Negative symptoms; Predictors; Psychosis; Verbal memory

PMID:
23489592
PMCID:
PMC4066735
DOI:
10.1016/j.psychres.2013.02.007
[Indexed for MEDLINE]
Free PMC Article
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