Format

Send to

Choose Destination
See comment in PubMed Commons below
Echocardiography. 2013 Sep;30(8):912-8. doi: 10.1111/echo.12156. Epub 2013 Mar 12.

Impaired coronary microvascular function and its association with disease duration and inflammation in patients with psoriasis.

Author information

1
Cardiology Department, Adana Teaching and Medical Research Center, Baskent University, Adana, Turkey.

Abstract

SUBJECTS:

Thirty-six patients with psoriasis and 56 healthy volunteers were included in this study.

METHODS:

Echocardiographic examination included transmitral peak flow velocities of the early phase (E) and late phase (A) of the mitral inflow, left ventricular myocardial velocity measurements, and coronary flow reserve (CFR) measurement.

RESULTS:

Baseline coronary diastolic peak flow velocity (DPFV) of left anterior descending artery (LAD) was significantly higher in the psoriasis group. However, hyperemic DPFV was slightly lower and CFR (2.19 ± 0.39 vs. 2.60 ± 0.31, P < 0.0001) was significantly lower in the psoriasis group than in the control group. CFR was significantly and inversely correlated with disease duration, Psoriasis Area and Severity Index (PASI) score, and hsCRP.

CONCLUSION:

CFR is decreased in patients with psoriasis, and it correlates to disease duration, PASI score, and inflammation.

KEYWORDS:

coronary flow reserve; echocardiography; psoriasis

PMID:
23488894
DOI:
10.1111/echo.12156
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Support Center