Format

Send to

Choose Destination
Oncoimmunology. 2013 Jan 1;2(1):e22892.

Tumor cell recognition by γδ T lymphocytes: T-cell receptor vs. NK-cell receptors.

Author information

1
Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa; Lisbon, Portugal.

Abstract

The dissection of the molecular mechanisms underlying tumor-cell recognition by γδ T-cells is crucial to improve their performance in cancer immunotherapy. Here, we discuss the controversy around the relative contributions of the γδ T-cell receptor (TCR) and natural killer receptors (NKRs) to tumor-cell targeting by γδ T cells.

KEYWORDS:

NK cell; NK receptor; NKG2D; T-cell receptor; γδ T cell

Supplemental Content

Full text links

Icon for Taylor & Francis Icon for PubMed Central
Loading ...
Support Center