The pentachlorophenol-dehalogenating Desulfitobacterium hafniense strain PCP-1

Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120319. doi: 10.1098/rstb.2012.0319. Print 2013 Apr 19.

Abstract

In this report, a complete description of Desulfitobacterium hafniense strain PCP-1 is presented. The D. hafniense strain PCP-1 was isolated from a methanogenic consortium for its capacity to dehalogenate pentachlorophenol (PCP) into 3-chlorophenol. This strain is also capable of dehalogenating several other chloroaromatic compounds and tetrachloroethene into trichloroethene. Four gene loci encoding putative chlorophenol-reductive dehalogenases (CprA2 to CprA5) were detected, and the products of two of these loci have been demonstrated to dechlorinate different chlorinated phenols. Strain PCP-1 was used in laboratory-scale bioprocesses to degrade PCP present in contaminated environments. Desulfitobacterium hafniense PCP-1 is an excellent candidate for the development of efficient bioprocesses to degrade organohalide compounds.

Publication types

  • Review

MeSH terms

  • Biodegradation, Environmental
  • Chlorophenols / metabolism
  • Desulfitobacterium / classification
  • Desulfitobacterium / enzymology
  • Desulfitobacterium / genetics
  • Desulfitobacterium / metabolism*
  • Gene Expression Regulation, Bacterial*
  • Gene Transfer, Horizontal
  • Genes, Bacterial*
  • Genetic Loci
  • Halogenation*
  • Pentachlorophenol / metabolism*
  • Phylogeny
  • RNA, Ribosomal, 16S / genetics
  • RNA, Ribosomal, 16S / metabolism
  • Species Specificity
  • Transcription, Genetic

Substances

  • Chlorophenols
  • RNA, Ribosomal, 16S
  • Pentachlorophenol
  • 3-chlorophenol