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Dev Neurorehabil. 2013 Jun;16(3):180-7. doi: 10.3109/17518423.2013.771221. Epub 2013 Mar 11.

Gross and fine motor skills in children treated for acute lymphoblastic leukaemia.

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1
Children's Cancer Centre, The Royal Children's Hospital, Melbourne, Australia.

Abstract

OBJECTIVE:

Chemotherapy treatment for acute lymphoblastic leukaemia (ALL) may disrupt motor development, with suggestions that gross and fine motor deficits are different depending on time since treatment.

METHODS:

Thirty-seven participants aged between 2.5 to 5 years at the time of diagnosis were assessed using the Movement Assessment Battery for Children, 2nd Edition (MABC-2) and the Bruininks-Oseretsky Test of Motor Proficiency, 2nd Edition, Short Form (BOT-2 SF), and divided into groups (i.e., months-off-treatment): (1) 0-12, (2) 13-24, and (3) 25-60 for comparison.

RESULTS:

MABC-2 and BOT-2 SF mean total scores fell within the average range. Twenty-six percent of the sample performed in the impaired range on the MABC-2. Group 2 had significantly lower Manual Dexterity scores than the normative population and lower BOT-2 SF scores than Group 1.

CONCLUSION:

Most children treated for ALL display appropriate motor skills, yet around a quarter experience general motor difficulties. Time-off-treatment did not affect the prevalence of motor impairments on any measure.

PMID:
23477341
DOI:
10.3109/17518423.2013.771221
[Indexed for MEDLINE]
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