Format

Send to

Choose Destination
See comment in PubMed Commons below
J Palliat Med. 2013 Apr;16(4):409-11. doi: 10.1089/jpm.2012.0424. Epub 2013 Mar 11.

Converting to transdermal fentanyl: avoidance of underdosing.

Author information

1
University of Georgia College of Pharmacy, Augusta, GA 30912, USA. abradley@gru.edu

Abstract

BACKGROUND:

Converting between the various opioid agents continues to be challenge for many practitioners. Specifically, variable recommendations for converting to the transdermal fentanyl patch may lead to confusion among clinicians and errors in dosing.

OBJECTIVE:

Our aim was to describe the inconsistencies among available opioid conversions with regard to transdermal fentanyl and to provide recommendations for safe and effective utilization of this product in patients with chronic pain.

RESULTS:

Available reports support the use of the morphine intravenous to oral ratio of 1:3 during the conversion to transdermal fentanyl product.

CONCLUSIONS:

Underdosing is an often overlooked complication of switching to transdermal fentanyl. Current recommendations for converting to transdermal fentanyl do not reflect contemporary clinical practice and should be reevaluated.

PMID:
23477303
DOI:
10.1089/jpm.2012.0424
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Mary Ann Liebert, Inc.
    Loading ...
    Support Center