Format

Send to

Choose Destination
See comment in PubMed Commons below
Med Intensiva. 2013 Dec;37(9):584-92. doi: 10.1016/j.medin.2012.12.005. Epub 2013 Mar 7.

Invasive device-related infections after heart surgery.

[Article in English, Spanish]

Author information

1
Servicio de Medicina Intensiva, Hospital del Mar, Barcelona, España. Electronic address: Falvarez@imas.imim.es.

Abstract

OBJECTIVE:

To analyze postoperative infections in critically ill patients undergoing heart surgery.

SETTING:

Intensive care units (ICUs).

DESIGN:

An observational, prospective, multicenter study was carried out.

PATIENTS:

Patients in the postoperative period of heart surgery admitted to the ICU and included in the ENVIN-HELICS registry between 2005 and 2011.

MAIN OUTCOME VARIABLES:

Mechanical ventilation associated pneumonia (MVP), urinary catheter-related infection (UCI), primary bacteremia (PB), PB related to vascular catheters (PB-VC) and secondary bacteremia.

RESULTS:

Of a total of 97,692 patients included in the study, 9089 (9.3%) had undergone heart surgery. In 440 patients (4.8%), one or more infections were recorded. Infection rates were 9.94 episodes of MVP per 1000 days of mechanical ventilation, 3.4 episodes of UCI per 1000 days of urinary catheterization, 3.10 episodes of BP-VC per 1000 days of central venous catheter, and 1.84 episodes of secondary bacteremia per 1000 days of ICU stay. Statistically significant risk factors for infection were ICU stay (odds ratio [OR] 1.18, 95%CI 1.16-1.20), APACHE II upon admission to the ICU (OR 1.05, 95%CI 1.03-1.07), emergency surgery (OR 1.67, 95%CI 1.13-2.47), previous antibiotic treatment (OR 1.38, 95%CI 1.04-1.83), and previous colonization by Pseudomonas aeruginosa (OR 18.25, 95%CI 3.74-89.06) or extended spectrum beta-lactamase producing enterobacteria (OR 16.97, 95%CI 5.4-53.2). The overall ICU mortality rate was 4.1% (32.2% in patients who developed one or more infections and 2.9% in uninfected patients) (P < .001).

CONCLUSIONS:

Of the patients included in the ENVIN-HELICS registry, 9.3% were postoperative heart surgery patients. The overall mortality was low but increased significantly in patients who developed one or more infection episodes.

KEYWORDS:

Cirugía cardiaca; ENVIN-HELICS registry; Factores de riesgo; Heart surgery; Infecciones relacionadas con dispositivos invasivos; Invasive device-associated infections; Registro ENVIN-HELICS; Risk factors

PMID:
23473741
DOI:
10.1016/j.medin.2012.12.005
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Ediciones Doyma, S.L.
    Loading ...
    Support Center