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Clin Oral Investig. 2014 Jan;18(1):59-66. doi: 10.1007/s00784-013-0953-z. Epub 2013 Mar 8.

Biomimetic treatment on dental implants for short-term bone regeneration.

Author information

1
Department of Materials Science and Metallurgical Engineering, Biomaterials, Biomechanics and Tissue Engineering Group, Technical University of Catalonia (UPC), Av. Diagonal 647, 08028, Barcelona, Spain, francesc.xavier.gil@upc.edu.

Abstract

OBJECTIVES:

The main purpose of this work was to assess the short-term bone regenerative potential of new osteoconductive implants. The novelty of the study lies in the analysis of the effectiveness of a novel two-step treatment which combines shot-blasting with a thermo-chemical treatment, at very short times after implant placement in a minipig model.

MATERIALS AND METHODS:

Three hundred twenty implants with four different surface treatments, namely bioactivated surfaces, micro-rough grit-blasted, micro-rough acid-etched and smooth as-machined titanium implants were placed into the bone of 20 minipigs. The percent of bone-to-implant contact was determined 3 days, 1, 2, 3 and 10 weeks after implant placement by histomorphometric analysis. Surface composition, topography and wettability of the implant specimens were analysed.

RESULTS:

The combination of shot-blasting and thermo-chemical treatment accelerated bone regeneration at early stages in comparison with all other treatments between day 3 and week 3 (p < 0.05). The value of osseointegration attained at week 2 was maintained until the end of the experiment without any significant changes (percent direct contact ≈ 85 %). This was mostly attributed to the ability of these implants to form in vivo a layer of apatitic mineral that coated the implant and could rapidly stimulate bone nucleation and growth from the implant surface.

CONCLUSIONS:

The surface quality resulting from this treatment on cpTi provided dental implants with a unique ability of rapid bone regeneration and osseointegration.

CLINICAL RELEVANCE:

This treatment represents a step forward in the direction of reducing the time prior to implant loading.

PMID:
23471738
DOI:
10.1007/s00784-013-0953-z
[Indexed for MEDLINE]

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