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Anal Chem. 2013 May 7;85(9):4203-14. doi: 10.1021/ac303053e. Epub 2013 Mar 21.

Metaproteomics: harnessing the power of high performance mass spectrometry to identify the suite of proteins that control metabolic activities in microbial communities.

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1
Oak Ridge National Laboratory, Oak Ridge, TN 37831-6131, USA. hettichrl@ornl.gov

Abstract

The availability of extensive genome information for many different microbes, including unculturable species in mixed communities from environmental samples, has enabled systems-biology interrogation by providing a means to access genomic, transcriptomic, and proteomic information. To this end, metaproteomics exploits the power of high-performance mass spectrometry for extensive characterization of the complete suite of proteins expressed by a microbial community in an environmental sample.

PMID:
23469896
PMCID:
PMC3696428
DOI:
10.1021/ac303053e
[Indexed for MEDLINE]
Free PMC Article
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