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Surg Clin North Am. 2013 Apr;93(2):329-40. doi: 10.1016/j.suc.2012.12.005. Epub 2013 Feb 8.

Surgical management of high-risk breast lesions.

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Department of Surgery, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.


High-risk lesions of the breast are lesions that confer an increased risk of breast cancer, either because of an increased probability of finding cancer associated with percutaneous biopsy findings or because of an increased probability of developing breast cancer over the long term. Atypical ductal hyperplasia found on percutaneous biopsy is generally excised, whereas lobular neoplasia lesions, including both atypical lobular hyperplasia and lobular carcinoma in situ, may be observed if radiologic and pathologic findings are concordant and there is no other high-risk lesion present.

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