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Nat Struct Mol Biol. 2013 Mar;20(3):274-81. doi: 10.1038/nsmb.2518.

DNA methylation dynamics in health and disease.

Author information

1
Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Hebrew University Medical School, Jerusalem, Israel. yehudit.bergman@huji.ac.il

Erratum in

  • Nat Struct Mol Biol. 2013 Oct;20(10):1236.

Abstract

DNA methylation is an epigenetic mark that is erased in the early embryo and then re-established at the time of implantation. In this Review, dynamics of DNA methylation during normal development in vivo are discussed, starting from fertilization through embryogenesis and postnatal growth, as well as abnormal methylation changes that occur in cancer.

Comment in

PMID:
23463312
DOI:
10.1038/nsmb.2518
[Indexed for MEDLINE]

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