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South Med J. 2013 Mar;106(3):196-200. doi: 10.1097/SMJ.0b013e318287fb0b.

Medical care of pregnant women in eastern North Carolina with human immunodeficiency virus.

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Department of Internal Medicine/Division of Infectious Diseases, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.



To assess the time lag between the diagnosis of human immunodeficiency virus (HIV) and the initiation of antiretroviral therapy (ART) in pregnant women.


A retrospective chart review of 105 deliveries from HIV-positive women from January 2001 to June 2009 was undertaken.


One hundred five HIV-infected pregnant women were identified and studied. Forty-eight women were diagnosed during the prenatal visit: 21 in the first trimester, 17 in the second trimester, and 10 in the third trimester. Forty-five had undetectable viral loads at delivery. The time lag between diagnosis of HIV and initiation of ART was 1 month for 31% and 3 months for 28.5%.


The time lag between diagnosis of HIV and initiation of ART was more than 1 month in 69% of the expectant mothers, which may have contributed to the failure in viral suppression. Implementation of HIV screening and a more effective means of communication between prenatal and HIV clinics are required to help reduce vertical transmission of the virus to neonates.

[Indexed for MEDLINE]

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