Format

Send to

Choose Destination
Chest. 2013 Mar;143(3):798-807. doi: 10.1378/chest.12-0938.

Cardiovascular disease in COPD: mechanisms.

Author information

1
Gartnavel General Hospital, Glasgow, Scotland.
2
MRC Centre for Inflammation Research, The Edinburgh University, Edinburgh, Scotland. Electronic address: w.macnee@ed.ac.uk.

Abstract

It is now well established that cardiovascular disease contributes significantly to both morbidity and mortality in COPD. Shared risk factors for cardiovascular disease and COPD, such as smoking, low socioeconomic class, and a sedentary lifestyle contribute to the natural history of each of these conditions. However, it is now apparent that alternative, novel mechanisms are involved in the pathogenesis of cardiovascular disease, and these may play an important role in driving the increased cardiovascular risk associated with COPD. In this article, we discuss the potential mechanisms that link COPD to an increased risk of cardiovascular disease.

PMID:
23460157
DOI:
10.1378/chest.12-0938
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center