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Neth Heart J. 2013 Apr;21(4):166-72. doi: 10.1007/s12471-013-0383-1.

Cardiopulmonary interactions during mechanical ventilation in critically ill patients.

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1
Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands, T.G.Cherpanath@amc.uva.nl.

Abstract

Cardiopulmonary interactions induced by mechanical ventilation are complex and only partly understood. Applied tidal volumes and/or airway pressures largely mediate changes in right ventricular preload and afterload. Effects on left ventricular function are mostly secondary to changes in right ventricular loading conditions. It is imperative to dissect the several causes of haemodynamic compromise during mechanical ventilation as undiagnosed ventricular dysfunction may contribute to morbidity and mortality.

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