Format

Send to

Choose Destination
See comment in PubMed Commons below
Bioinformatics. 2013 May 1;29(9):1235-7. doi: 10.1093/bioinformatics/btt104. Epub 2013 Mar 1.

RCPedia: a database of retrocopied genes.

Author information

1
Centro de Oncologia Molecular, Hospital Sírio-Libanês, São Paulo 01308-060, Brazil.

Abstract

MOTIVATION:

Retrocopies are copies of mature RNAs that are usually devoid of regulatory sequences and introns. They have routinely been classified as processed pseudo-genes with little or no biological relevance. However, recent findings have revealed functional roles for retrocopies, as well as their high frequency in some organisms, such as primates. Despite their increasing importance, there is no user-friendly and publicly available resource for the study of retrocopies.

RESULTS:

Here, we present RCPedia, an integrative and user-friendly database designed for the study of retrocopied genes. RCPedia contains a complete catalogue of the retrocopies that are known to be present in human and five other primate genomes, their genomic context, inter-species conservation and gene expression data. RCPedia also offers a streamlined data representation and an efficient query system.

AVAILABILITY AND IMPLEMENTATION:

RCPedia is available at http://www.bioinfo.mochsl.org.br/rcpedia.

PMID:
23457042
PMCID:
PMC3634192
DOI:
10.1093/bioinformatics/btt104
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems Icon for PubMed Central
    Loading ...
    Support Center