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Physiology (Bethesda). 2013 Mar;28(2):125-34. doi: 10.1152/physiol.00042.2012.

Endothelial fatty acid transport: role of vascular endothelial growth factor B.

Author information

1
Karolinska Institute, Stockholm, Sweden.

Abstract

Dietary lipids present in the circulation have to be transported through the vascular endothelium to be utilized by tissue cells, a vital mechanism that is still poorly understood. Vascular endothelial growth factor B (VEGF-B) regulates this process by controlling the expression of endothelial fatty acid transporter proteins (FATPs). Here, we summarize research on the role of the vascular endothelium in nutrient transport, with emphasis on VEGF-B signaling.

PMID:
23455771
PMCID:
PMC3768092
DOI:
10.1152/physiol.00042.2012
[Indexed for MEDLINE]
Free PMC Article

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