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Genome Biol. 2013 Feb 26;14(2):107. doi: 10.1186/gb-2013-14-2-107.

A CRISPR way to engineer the human genome.

Abstract

RNA-guided genome engineering based on the type II prokaryotic CRISPR/Cas system provides an efficient and versatile method for targeted manipulation of mammalian genomes.

PMID:
23448668
PMCID:
PMC3663103
DOI:
10.1186/gb-2013-14-2-107
[Indexed for MEDLINE]
Free PMC Article

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