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Scand J Clin Lab Invest. 2013 Apr;73(3):253-61. doi: 10.3109/00365513.2013.769625. Epub 2013 Feb 28.

Population-based pediatric reference intervals for hematology, iron and transferrin.

Author information

1
Department of Clinical Chemistry, County Hospital of Falun, Falun, Sweden.

Abstract

Reference intervals are crucial decision-making tools aiding clinicians in differentiating between healthy and diseased populations. However, for children such values often are lacking or incomplete. Blood samples were obtained from 689 healthy children, aged 6 months to 18 years, recruited in day care centers and schools. Hematology and anemia analytes were measured on the Siemens Advia 2120 and Abbott Architect ci8200 platforms (hemoglobin, erythrocyte volume fraction [EVF], erythrocytes, mean corpuscular volume [MCV], mean corpuscular hemoglobin [MCH], mean corpuscular hemoglobin concentration [MCHC], reticulocytes, leukocytes, lymphocytes, monocytes, neutrophils, eosinophils, basophils, platelets, iron, transferrin, transferrin saturation). Age- and gender-specific pediatric reference intervals were defined by calculating 2.5th and 97.5th percentiles. The data generated is primarily applicable to a Caucasian population, but could be used by any laboratory if verified for the local patient population.

PMID:
23448533
DOI:
10.3109/00365513.2013.769625
[Indexed for MEDLINE]

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