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J Econ Entomol. 2013 Feb;106(1):366-74.

Insecticide resistance and malaria vector control: the importance of fitness cost mechanisms in determining economically optimal control trajectories.

Author information

1
Organisation for Economic Cooperation and Development (OECD), 2, Rue André Pascal, 75775, Paris, France. zack.brown@oecd.org

Abstract

The evolutionary dynamics of insecticide resistance in harmful arthropods has economic implications, not only for the control of agricultural pests (as has been well studied), but also for the control of disease vectors, such as malaria-transmitting Anopheles mosquitoes. Previous economic work on insecticide resistance illustrates the policy relevance of knowing whether insecticide resistance mutations involve fitness costs. Using a theoretical model, this article investigates economically optimal strategies for controlling malaria-transmitting mosquitoes when there is the potential for mosquitoes to evolve resistance to insecticides. Consistent with previous literature, we find that fitness costs are a key element in the computation of economically optimal resistance management strategies. Additionally, our models indicate that different biological mechanisms underlying these fitness costs (e.g., increased adult mortality and/or decreased fecundity) can significantly alter economically optimal resistance management strategies.

PMID:
23448053
PMCID:
PMC3969818
[Indexed for MEDLINE]
Free PMC Article

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