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Adv Healthc Mater. 2013 Sep;2(9):1213-8. doi: 10.1002/adhm.201200473. Epub 2013 Feb 28.

Functional living biointerphases.

Author information

1
Abengoa Research, Abengoa, Campus Palmas Altas, Sevilla, Spain.

Abstract

Lactococcus lactis is modified to express a fibronectin fragment (FNIII₇₋₁₀) as a membrane protein. This interphase, based on a living system, can be further exploited to provide spatio-temporal factors to direct cell function at the material interface. This approach establishes a new paradigm in biomaterial surface functionalization for biomedical applications.

KEYWORDS:

bacteria; cell adhesion; fibronectin; integrin; interface

PMID:
23447109
DOI:
10.1002/adhm.201200473
[Indexed for MEDLINE]

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