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Chem Commun (Camb). 2013 Apr 11;49(28):2879-81. doi: 10.1039/c3cc38804b.

RNA-templated DNA origami structures.

Author information

1
Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Yoshida-ushinomiyacho, Sakyo-ku, Kyoto 606-8501, Japan. endo@kuchem.kyoto-u.ac.jp

Abstract

Using the RNA transcript as a template, RNA-templated DNA origami structures were constructed by annealing with designed DNA staple strands. RNA-templated DNA origami structures were folded to form seven-helix bundled rectangular structures and six-helix bundled tubular structures. The chemically modified RNA-DNA hybrid origami structures were prepared by using RNA templates containing modified uracils.

PMID:
23446278
DOI:
10.1039/c3cc38804b
[Indexed for MEDLINE]

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