Format

Send to

Choose Destination
Indian J Cancer. 2012 Oct-Dec;49(4):364-72. doi: 10.4103/0019-509X.107735.

Chemistry and toxicology of smokeless tobacco.

Author information

1
Retired from Department of Carcinogenesis, Cancer Research Institute, Tata Memorial Center, Parel, Mumbai, Maharashtra, India. rajani.bhisey@gmail.com

Abstract

In most parts of the world, tobacco is used for smoking, whereas, in India, tobacco is used for smoking as well as in diverse smokeless forms. Absorption of toxic and carcinogenic chemicals in tobacco and other ingredients added to various products are causally associated with several non-communicable diseases including cancer, especially oral cancer, which is the leading cancer among men and the third most common cancer among women in India. This article highlights the toxicity, mutagenecity and carcinogenic effects of hazardous chemicals present in smokeless tobacco products. This endeavor was based on the extensive review of literature from various sources. The SLT products have influence on cellular metabolism, ability to cause DNA damage, and cancer in experimental animals. It is, therefore, essential to consider the collective role of chemical constituents of SLT products in the causation of adverse effect on human health.

PMID:
23442400
DOI:
10.4103/0019-509X.107735
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Medknow Publications and Media Pvt Ltd
Loading ...
Support Center