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Clin Ophthalmol. 2013;7:363-5. doi: 10.2147/OPTH.S37443. Epub 2013 Feb 18.

Multifocal choroiditis following simultaneous hepatitis A, typhoid, and yellow fever vaccination.

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1
Havener Eye Institute, The Ohio State University, Columbus, OH, USA.

Abstract

The paper describes the first reported case of multifocal choroiditis following simultaneous hepatitis-A, typhoid, and yellow fever vaccinations. A 33-year-old male developed sudden onset of flashing lights and floaters in his right eye 3 weeks following hepatitis A, typhoid, and yellow fever vaccinations. Fundus examination and angiography confirmed the presence of multiple peripheral chorioretinal lesions. These lesions demonstrated characteristic morphologic changes over a period of 8 weeks which were consistent with a diagnosis of self-resolving multifocal choroiditis. Vaccine-induced intraocular inflammation has been described infrequently. We demonstrate the first case of self-resolving multifocal choroiditis following simultaneous administration of hepatitis A, yellow fever, and typhoid immunizations.

KEYWORDS:

hepatitis A; multifocal choroiditis; typhoid; vaccination; yellow fever

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