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Mol Cell. 2013 Feb 21;49(4):583-90. doi: 10.1016/j.molcel.2013.01.029.

The coming age of complete, accurate, and ubiquitous proteomes.

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1
Max Planck Institute of Biochemistry, 82152 Martinsried, Germany. mmann@biochem.mpg.de

Abstract

High-resolution mass spectrometry (MS)-based proteomics has progressed tremendously over the years. For model organisms like yeast, we can now quantify complete proteomes in just a few hours. Developments discussed in this Perspective will soon enable complete proteome analysis of mammalian cells, as well, with profound impact on biology and biomedicine.

PMID:
23438854
DOI:
10.1016/j.molcel.2013.01.029
[Indexed for MEDLINE]
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